At the Centre for Liver Research and Diagnostics, our cancer research initiatives reflect a focused and evolving commitment to unraveling the molecular, genetic, and clinical complexities of cancer. While this theme represents a more specialized segment of our broader research portfolio, it encompasses a meaningful body of work that advances understanding in key areas of oncology.
Our investigations have primarily concentrated on gastric and hepatic carcinomas, with a strong emphasis on identifying and validating serum biomarkers such as pepsinogen in stomach cancer patients. These studies have yielded valuable insights into the biochemical alterations associated with malignancies, contributing to the early detection and differentiation of cancer types.
We have also explored the genetic and immunological underpinnings of cancer. Our research into the expression of HLA-DR antigens in gastric carcinoma has suggested potential links between immune system markers and cancer susceptibility. This aligns with our broader goal of integrating immunogenetics into cancer diagnostics and advancing the field of personalized medicine.
Another significant area of our work involves examining the association between blood group antigens and cancer risk, particularly in gastrointestinal malignancies. These studies aim to uncover hereditary and immunological factors that may influence cancer development, offering a foundation for risk stratification and targeted screening strategies.
To deepen our understanding of cancer pathophysiology and evaluate emerging therapies, we have developed and utilized experimental models. These models have been instrumental in studying tumor behavior, assessing drug responses, and testing the efficacy of novel treatment modalities.
Our cancer research is inherently multidisciplinary, bridging clinical observations with molecular biology, immunology, and genetics. Through this integrated approach, we continue to contribute to the growing body of knowledge aimed at improving cancer diagnosis, prognosis, and therapeutic outcomes.
