Check Our Research Studies on
Nanotechnology
The Centre for Liver Research & Diagnostics has been at the forefront of integrating nanotechnology into biomedical research, with a strong focus on translational applications. This curated collection of 21 research publications showcases our multidisciplinary efforts in developing innovative nanomaterials and applying them across diverse domains such as drug delivery, cancer therapy, biosensing, and diagnostics. Spanning from 2014 to 2021, these studies reflect our commitment to advancing healthcare through nanoscale science.
The benefits of this research are profound. From enhancing the precision of cancer treatments and reversing drug resistance, to enabling non-invasive diagnostics and pioneering green synthesis of biocompatible nanomaterials, each study contributes to the evolving landscape of precision medicine. These contributions not only enrich the scientific community but also lay the groundwork for next-generation therapies and diagnostic platforms that are safer, faster, and more effective.
Analyst. 2021 Jul 7
Genotyping simplified: rationally designed antisense oligonucleotide-mediated PCR amplification-free colorimetric sensing of viral RNA in HCV genotypes 1 and 3.Authors: Mohammed AS, Balapure A, Khan AA, Khaja MN, Ganesan R, Dutta JR
Advanced Therapeutics, 2020; 900205:1-18
Glycemic Stimulation with Conducting Substrate Enhances Insulin Secretion of Transdifferentiated Human Hepatic Progenitor Cells Adherent on Nanostructured TiO2 Chips for Hyperglycemia Reversal in Diabetic Mice without Immunosuppression.Authors: Vishwakarma SK, Jaiswal J, Park KH, Lakkireddy C, Raju N, Bardia A, Habeeb MA, Paspala SAB, Khan AA, Dhayal M
Applied Nanoscience, 2018; 8(6):1493–1504
Bimetallic redox nanoprobe enhances the therapeutic efficacy of hyperthermia in drug-resistant cancer cells.Authors: Vishwakarma SK, Lakkireddy C, Marjan T, Fatima A, Bardia A, Paspala SAB, Habeeb MA, Khan AA
Applied Nanoscience, 2018; 8(1):115-124
Real-time cellular and molecular dynamics of bi-metallic self-therapeutic nanoparticle in cancer cells.Authors: Vishwakarma SK, Bardia A, Lakkireddy C, Paspala SAB, Habeeb MA, Khan AA
Clinical Hemorheology and Microcirculation, 2018; 69(1-2):197-205
In vitro hemocompatability evaluation of gold nanoparticlesn capped with Lactobacillus plantarum derived lipase.Authors: Khan I, Vishwakarma SK, Khan AA, Ganesan R, Duttaa JR
Scientific Reports, 2017; 7:8539
Use of biocompatible sorafenib-gold nanoconjugates for reversal of drug resistance in human hepatoblastoma cells.Authors: Vishwakarma SK, Sharmila P, Bardia A, Chandrakala L, Raju N, Sravani G, Sastry BVS, Habeeb MA, Khan AA, Dhayal M
RSC Adv., 2016, 6, 100487-100493
Cu-Catalyzed ligand-free synthesis of rosuvastatin based novel indole derivatives as potential anticancer agents.Authors: K. Shiva Kumar, Bandari Rajesham, Meesa Siddi Ramulu, Boyapally Bhaskar, Surjya Narayan Dash, Mohd Ashraf Ashfaq, Raju Nagarapu, Aleem Ahmed Khan, Sanna Lehtonen, Manojit Pal
RSC Adv., 2016; 54
AlCl3-mediated heteroarylation-cyclization strategy: one-pot synthesis of fused quinoxalines containing the central core of Lamellarin D.Authors: K. Shiva Kumar, Siddi Ramulu Meesa, Bandari Rajesham, Boyapally Bhasker, Mohd Ashraf Ashfaq, Aleem Ahmed Khan, Sagurthi Someswar Rao, Manojit Pal
Biomedical Physics & Engineering Express, 2016; 2:025010
Super paramagnetic iron oxide and gadolinium (FeGdO3) nanopowder synthesized by hydrolytic approach passes high level of biocompatibility and MRI-based dual contrast property for competent molecular imaging and therapeutic interventions.Authors: Athar T, Vishwakarma SK, Bardia A, Khan AA
Applied Nanoscience, 2016; 6(5):767–777
Green approach for the synthesis and characterization of ZrSnO4 nanopowder.Authors: Athar T, Vishwakarma SK, Bardia A, Alabass R, Alqarlosy A, Khan AA
Applied Nanoscience, 2016; 6(6):913–922
Synthesis of nanostructured framework of novel ZnBaO2 nanopowder via wet chemical approach and hepatocytotoxicity response.Authors: Athar T, Vishwakarma SK, Alabass R, Alqarlosy A, Khan AA
Neurology India, 2015; 63(3):460-61
Magnetic nanoparticle tagged stem cell transplantation in spinal cord injury: A promising approach for targeted homing of cells at the lesion site.Authors: Vishwakarma SK, Bardia A, Paspala SAB, Khan AA
Sensors and Materials, 2015; 27(7): 563–573
Green Synthesis of NiSnO3 Nanopowder and Its Application as a Hydroquinone Electrochemical Sensor.Authors: Taimur Athar, Magdy Abdelaal, Zeenat Khatoon, Amit Kumar, Alabass Razzaq, Aleem Ahmed Khan, Hassan Fouad, Shafeeque Ahmed Ansari and Zubaida Amin Ansari
Journal of Bionanoscience, 2015; 9:1-10
Soft chemical approach for the synthesis, characterization and safety assessment of novel Fe3AlO6 nanopowder in human neural precursor cells.Authors: Taimur Athar, Sandeep K Vishwakarma, Avinash Bardia, Syed AB Paspala, Md. Aejaz Habeeb, Aleem A Khan
Applied Nanoscience, 2015
Green approach for the synthesis and characterization of ZrSnO4 nanopowder.Authors: Athar Taimur, Vishwakarma Sandeep, Bardia Avinash, Alabass Razzaq, Alqarlosy Ahmed, Khan Aleem
Applied Nanoscience, 2015
Synthesis of nanostructured framework of novel ZnBaO2 nanopowder via wet chemical approach and hepatocytotoxicity response.Authors: Athar Taimur, Vishwakarma Sandeep, Alabass Razzaq, Alqarlosy Ahmed, Khan Aleem
Rev. Adv. Sci. Eng. 4, 258-270 (2015)
A Review on Synthesis of Nanostructured Metal Oxide Powder via Soft Chemical Approach.Authors: Athar Taimur, Ahmed, Khan Aleem, Vishwakarma Sandeep, Alabass Razzaq, Alqarlosy Ahmed
Materials Focus, 2014; 3(5):378-381
Low-Temperature Growth and Properties of NiO Nano Sheets Decorated with Small NiO Nano Rods via Soft Chemical Process.Authors: Athar T, Mahamad SSS; Khan AA
Materials Focus, 2014; 3(5):341-344
Facile Synthesis of ZnO Nanosheets with Controlled Functional Properties via Soft-Chemical Process.Authors: Athar T, Mahamad SSS; Khan AA
Materials Focus, 2014; 3(5):397-400
Soft Chemical Process for Synthesis of CdO Nanoparticles.Authors: Athar T, Mahamad SSS; Khan AA
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Impact of our Research
At the Centre for Liver Research & Diagnostics, our research in Nanotechnology exemplifies our commitment to pioneering innovations that bridge materials science with biomedical applications. Spanning over a decade, our 21 peer-reviewed publications explore the synthesis, characterization, and application of nanomaterials in healthcare, diagnostics, and therapeutics. Our nanotechnology research is categorized into four key domains, each contributing uniquely to the advancement of precision medicine and translational science:
Nanomedicine and Drug Delivery
Our research explores how nanostructured platforms and biocompatible materials can enhance therapeutic outcomes. From boosting insulin secretion in diabetic models to stem cell homing and reversing drug resistance, these innovations offer promising, non-invasive solutions for chronic disease management.
2016 – 2020
Cancer Nanotechnology
Our work in this area highlights the use of hyperthermia-enhanced therapies, bi-metallic nanoparticles, and real-time molecular imaging to combat cancer. These approaches offer new hope for precision oncology, enabling more effective and less toxic treatment modalities in cancer treatment efficacy.
2016 – 2018
Biosensing and Diagnostics
Our researchers have pioneered PCR-free colorimetric assays and electrochemical sensors using nanomaterials. These technologies enable rapid, accurate, and cost-effective diagnostics, with applications in infectious disease detection and environmental monitoring, nanoscale sensors and tools for detecting viral RNA.
2015 – 2021
Nanomaterials Synthesis and Characterization
Emphasizing green and soft chemical synthesis, our work has led to the development of biocompatible nanomaterials with tailored properties. These materials are evaluated for safety, functional performance, and potential use in imaging, electronics, and therapeutic systems.
2014 – 2017