Check Our Research Studies on
Molecular Genetics and Immunology
The Centre for Liver Research & Diagnostics is proud to present a curated collection of 33 research publications under the domain of Molecular Genetics and Immunology. These studies reflect our ongoing commitment to advancing scientific knowledge in areas critical to human health, including autoimmune disorders, cancer biology, infectious diseases, and molecular diagnostics. Each paper represents a step forward in understanding the complex interplay between genes, immune responses, and disease mechanisms.
The benefits of this research are far-reaching: from identifying novel biomarkers for early diagnosis, to uncovering genetic polymorphisms that influence disease progression, and developing targeted therapeutic strategies. Collectively, these contributions not only enrich the global scientific community but also support our mission to translate research into real-world clinical impact—improving patient outcomes and shaping the future of personalized medicine.
Mitochondrion (2024): 101967
Molecular basis of sepsis: A New insight into the role of mitochondrial DNA as a damage-associated molecular pattern.Authors: Bushra, Ahmed, Shaik Iqbal Ahmed, Safia Begum, Md Safwaan Habeeb, Tahmeen Jameel, and Aleem Ahmed Khan
Eur J Trauma Emerg Surg. 2024 Jun;50(3):897-904
Assessment of soluble thrombomodulin and soluble endoglin as endothelial dysfunction biomarkers in seriously ill surgical septic patients: correlation with organ dysfunction and disease severity.Authors: Khan MAO, Suvvari TK, Harooni SAS, Khan AA, Anees S, Bushra
International Journal of All Research Education & Scientific Methods. 12. 2486
Estimation of Cell free Circulatory Neutrophil Extracellular Traps (NETS) and hypoxic inducible factor (HIF1 alpha) in ischemic brain patients.Authors: Fathima, Nusrath & Khan, Dr. Aleem
Scholastic Medical Sciences, vol. 2, iss. 5, pp. 1-4, 2024.
Mitochondrial Potential and ND1 gene Expression Analysis in Platelets for Quality Assessment.Authors: Yeshwanth AN, Jabeen MS, Khan AA, Fathima N
Mitochondrion 68 (2023): 114-124
Simultaneous extraction and quantification of circulating mitochondrial and nuclear DNA using a single plasma sample to predict specific molecular diagnostic implications.Authors: Vishwakarma, Sandeep Kumar, Nusrath Fathima, Santosh K. Tiwari, and Aleem Ahmed Khan
J Cytol Genet. 2023 Oct;24(NS):87-99
Assessing the expression of peptidyl arginine deiminase type 4 as a neutrophil extracellular trap marker in sepsis and septic shock patients.Authors: Bushra, Safia B, Iqbal AS, Pawar SC, Khan AA
Indian Journal of Clinical Biochemistry 38, no. 1 (2023): 110-119
Association of Angiotensin II Type 1 Receptor (AT1R) Gene Polymorphism with Angiotensin II Serum Levels in Patients with Essential Hypertension.Authors: Prasad, M., D. Rajarajeswari, K. Ramlingam, R. Viswakumar, B. Suneel, Jyothi Conjeevaram, P. Aruna, Nusrath Fathima, Sandeep Kumar Vishwakarma, and Aleem Ahmed Khan
Adv Biores. 2023 Sep;14(5):218-227
Differential expression of Claudin-3 and Claudin-4 in endometriosis.Authors: Safia B, Iqbal AS, Bushra, Pawar SC, Khan AA
Journal of Pharmacy and Bioallied Sciences 15, no. Suppl 2 (2023): S1040-S1042
In vitro Isolation and Characterization of Multipotent Postnatal Stem Cells from Human Dental Pulp: An Approach for Regeneration of Neural Crest Tissue.Authors: Fatima, Nikhat, Aleem A. Khan, and Sandeep K. Vishwakarma
Human Gene 34 (2022): 201081
Implication of circulating microRNA-21 as a potential non-invasive diagnostic predictor of prostate cancer patients.Authors: Ahmed, Shaik Iqbal, Shahana Sarwar, Hemant Verma, Rahul Verma, Chandrakala Lakkireddy, Mohammed Abdul Majid Adil, and Aleem Ahmed Khan
Indian J Clin Biochem 2021 Jun 15:1-7. Epub 2021 Jun 15
Status of Vitamin D Receptor Gene Polymorphism and 25-Hydroxy Vitamin D Deficiency with Essential Hypertension.Authors: M Prasad, D Rajarajeswari, P Aruna, K Ramalingam, R Viswakumar, Nusrath Fathima, Sandeep Kumar Vishwakarma, Aleem Ahmed Khan
Indian Journal of Cardiovascular Disease in Women - WINCARS 2020; 5(01): 08-14.
Quantitative Expression Analysis of Circulating miRNAs Reveals Significant Association with Cardiovascular Pathogenesis in Women.Authors: Chandrakala Lakkireddy, Siddharth Rout, Shaik Iqbal Ahmed, Nooruddin Owaisi, Avinash Bardia, Nagarapu Raju, Sandeep Kumar Vishwakarma, Aleem Ahmed Khan
European Journal of Immunology, 2019; 49(2):277-289
Activation of integrated stress response pathway regulates IL-1β production through post-transcriptional and translational reprogramming in macrophages.Authors: Naz S, Battu S, Khan RA, Afroz S, Giddaluru J, Vishwakarma SK, Satti V, Habeeb MA, Khan AA, Khan N
Meta Gene, 2019; 20:100548
Regulation of heat shock protein-70 gene transcripts in breast cancer cells during hypo and hyperthermia exposure.Authors: Annamaneni S, Vishwakarma SK, Meka PB, Khan AA, Nallari P
PLoS Biol 2018 04 5;16(4):e2005317
Avery August, Seyed Ehtesham Hasnain, Nooruddin Khan. Amino acid starvation sensing dampens IL-1β production by activating riboclustering and autophagy.Authors: Srikanth Battu, Sumbul Afroz, Jeevan Giddaluru, Saima Naz, Weishan Huang, Saratchandra Singh Khumukcham, Rafiq Ahmad Khan, Saleem Yousuf Bhat, Insaf Ahmed Qureshi, Bramanandam Manavathi, Aleem Ahmed Khan
Cellular Immunology, 334 (2018) 42–48
Transcriptome meta-analysis identifies immune signature comprising of RNA binding proteins in ulcerative colitis patients.Authors: Naz S, Khan RA, Giddaluru J, Battu S, Vishwakarma SK, Subahan M, Satti V, Khan N, Khan AA
International Journal of Immunogenetics, 2018; 45(4):190-200
Association of CD14 and macrophage migration inhibitory factor gene polymorphisms with inflammatory microRNAs expression levels in ankylosing spondylitis and polyarthralgia.Authors: Vishwakarma SK,Lakkireddy C, Sravani G, Sastry BVS, Raju N, Ahmed SI, Khan AA, Owaisi N, Jaisawal A, Khan MA, Khan AA
Frontiers in Immunology, 2017; 2(8):74
A Comprehensive Gene Expression Meta-analysis Identifies Novel Immune Signatures in Rheumatoid Arthritis Patients.Authors: Afroz S, Giddaluru J, Vishwakarma SK, Naz S, Khan AA, Khan N
International Journal of Cardiology and Heart Health, 2017; 1:3, 40-46
The Role of N Terminal Pro-BNP in Assessing Severity of Coronary Artery Disease: A Prospective Study.Authors: Raut S, Mohapatra CS, Wasay A, Owaisi N, Khan AA
Inflammation, 2016; 39(3):1198-1204
Genetic polymorphisms of X-ray repair cross-complementing group 1 and apurinic/apyrimidic endonuclease-1 in chronic obstructive pulmonary disease.Authors: Bardia A, Vishwakarma SK,Chandrakala L, Raju N, Iqbal S, Sravani G, Lavanya N, Begum N, Usma N, Nallari P, Baderuzzaman, Ahmed SM, Hasan A, Khan AA
Tumour Biology, 2016; 37(5):6905-12
Influence of BCL2-938 C>A promoter polymorphism and BCL2 gene expression on the progression of breast cancer.Authors: Bhushann MP, Jarjapu S, Vishwakarma SK, Nanchari SR, Cingeetham A, Annamaneni S, Mukta S, Triveni B, Satti V
Asian Pacific Journal of Cancer Prevention, 2015; 16(12):4965-69
LCN2 Promoter Methylation Status as Novel Predictive Marker for Microvessel Density and Aggressive Tumor Phenotype in Breast Cancer Patients.Authors: Bhushann MP, Jarjapu S, Nanchari SR, Vishwakarma SK, Edathara PM, Gorre M, Cingeetham A, Vuree S, Annamaneni S, Dunna NR, Mukta S, B T, Satti V
PLOS ONE. 2014; 9: e108562
Haplotype Analyses of DNA Repair Gene Polymorphisms and Their Role in Ulcerative Colitis.Authors: Bardia A, Tiwari SK, Vishwakarma SK, Habeeb MA, Nallari P, Sultana SA, Pasha SA, Reddy YP, Khan AA
International Journal of Recent Scientific Research, 2014; 5(4):845-54
Development of an appropriate in vitro culture model system for understanding of hepatitis c virus pathogenesis.Authors: Nagarapu R, Vishwakarma SK, Rahamathulla S, Habeeb MA, Khan AA
International Journal of Science and Research (IJSR), 2014; 3(6):564-71
Human ATP Binding Cassette (ABC) Transporters: A Phylogenetic Investigation.Authors: Vishwakarma SK, Paspala SAB, Khan AA
IOSR Journal of Pharmacy Volume 4, Issue 1 (January 2014), PP 67-73
Varied Virological Response of Patients with Chronic Hepatitis C against the Treatment of Pegylated Interferon- α and Ribavirin.Authors: Neha Tabassum, Zeba Raheem, Anwar Yasmin, Mohammed Nomaan Ilyas, Arshad Hussain Mohd, Raju Nagarapu, Sandeep K Vishwakarma, Avinash Bardia, Syed Rahamathulla, Mohd. Aejaz Habeeb, Aleem Ahmed Khan
International Journal of Advanced Research (2013), Volume 1, Issue 8, 439-449
A meta-analysis of genotyping methods and nucleotide variation in Hepatitis C Virus.Authors: Raju Nagarapu, Syed Rahamathulla, Sandeep Kumar Vishwakarma, Srivatsan Kunnavakkam Vinjimuri, Ramachandra Rao VV, Pathan K Khanum, Mohammed Aejaz Habeeb, Vishnu Priya Satti, Mohammed Nanne Khaja, Aleem Ahmed Khan
International Journal of Advanced Research (2013), Volume 1, Issue 10, 139-144
Monocyte Migration and Inflammatory Response in the Pathogenesis of Rheumatoid Arthritis.Authors: Mazaharuddin A khan, Avinash Bardia, Santosh K. Tiwari, Sandeep K Vishwakarma, M. Phanibhushan, G. Lakshmi Lavanya, S. Vishnupriya, Aleem A. Khan
International Journal of Advanced Research (2013), Volume 1, Issue 9, 800-803
Urinary Pepsinogen Levels in Peptic Ulcer: A Subclinical Marker for Better Diagnosis and Prediction of Risk Factors of Acid Peptic Disease.Authors: Mahabubunnisa Begum, Baderuzzaman, Sandeep Kumar vishwakarma, Nusrath Fathima, Syed Rahamathulla, Aleem A Khan
Advances in Cancer: Research & Treatment, 2013. DOI:10.5171/2013.649799
Recent Approaches and Novel Therapeutic Targets in Human Glioma.Authors: Sandeep K Vishwakarma, Avinash Bardia, Santosh K Tiwari, Syed Ameer Basa Paspala, Aleem Ahmed Khan
Open Journal of Immunology. 2012; 2: 144-148
The epidemiology and prevalence of Ulcerative colitis in the South of India.Authors: Sivaram G, Santosh K. Tiwari, Avinash Bardia, S. Vishnupriya, Md. Aejaz Habeeb, Aleem A. Khan
International Journal of Advanced Research (2013), Volume 1, Issue 9, 800-803
Urinary Pepsinogen Levels in Peptic Ulcer: A Subclinical Marker for Better Diagnosis and Prediction of Risk Factors of Acid Peptic Disease.Authors: Mahabubunnisa Begum, Baderuzzaman, Sandeep Kumar vishwakarma, Nusrath Fathima, Syed Rahamathulla, Aleem A Khan
Inflammation Research. 2012; 6:359-365
Functional polymorphisms in XRCC-1 and APE-1 contribute to increased apoptosis and risk of ulcerative colitis.Authors: Avinash Bardia, Santosh K. Tiwari, Sivaram Gunisetty, Farha Anjum, Pratibha Nallari, Md. Aejaz Habeeb, Aleem A. Khan
Innate Immunity. 2011; 17(6):526-31
Association of genetic variants of Mannan Binding Lectin-2 gene, MBL levels and function in Ulcerative Colitis and Crohn’s Disease.Authors: Sivaram G, Santosh K. Tiwari, Avinash Bardia, Manoj G, Santhosh Kumar B, Saikant R, Md. Aejaz Habeeb, Aleem A. Khan, CM Habibullah
Discuss With Us For Your Research Needs
Whether you’re starting a new research project or preparing for publication, our team is here to support you every step of the way. From topic selection and methodology guidance to journal recommendations and formatting assistance, we offer personalized consultations to help you achieve your academic goals. Let’s collaborate to turn your ideas into impactful research.
Leave Your Message
Impact of our Research
At the Centre for Liver Research & Diagnostics, our research in Molecular Genetics and Immunology reflects a deep commitment to advancing precision medicine through cutting-edge science. Our multidisciplinary team has produced a robust body of work 33 peer-reviewed publications, spanning key areas of human health and disease. We have organized our research into four thematic domains, each contributing uniquely to the understanding, diagnosis, and treatment of complex diseases:
0
%
Inflammatory & Autoimmune Disorders
By decoding the molecular pathways of inflammation, we are paving the way for more precise & effective treatments for autoimmune conditions.
2011 - 2019
0
%
Cancer & Genetic Polymorphisms
Our work bridges genetics and oncology, offering insights that can transform cancer care through precision medicine.
2013 - 2019
0
%
Infectious Diseases & Immunogenetics
Understanding how our genes interact with pathogens is key to developing next-generation treatments for infectious diseases.
2013 - 2024
0
%
Molecular Diagnostics & Biomarkers
We are redefining diagnostics by turning molecular signals into actionable clinical insights, shaping the future of personalized diagnostics
2016 - 2024